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C624

Recombinant Human PAF acetylhydrolase/LDL-PLA(2)

10ug

1200

1080

现货

国产

C624

Recombinant Human PAF acetylhydrolase/LDL-PLA(2)

50ug

3520

3168

现货

国产

C624

Recombinant Human PAF acetylhydrolase/LDL-PLA(2)

500ug

12320

11088

现货

国产

C624

Recombinant Human PAF acetylhydrolase/LDL-PLA(2)

1mg

17600

15840

现货

国产

C624

Recombinant Human Phospholipase A2, Group VII/PLA2G7

10ug

1200

1080

现货

国产

C624

Recombinant Human Phospholipase A2, Group VII/PLA2G7

50ug

3520

3168

现货

国产

C624

Recombinant Human Phospholipase A2, Group VII/PLA2G7

500ug

12320

11088

现货

国产

C624

Recombinant Human Phospholipase A2, Group VII/PLA2G7

1mg

17600

15840

现货

国产

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  • Catalog# C624
    Source HEK293
    Description Recombinant Human Platelet-Activating Factor Acetylhydrolase/PAFAH is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Phe22-Asn441) of Human PAFAH fused with a polyhistidine tag at the C-terminus.
    Names Platelet-Activating Factor Acetylhydrolase, PAF Acetylhydrolase, 1-Alkyl-2-Acetylglycerophosphocholine Esterase, 2-Acetyl-1-Alkylglycerophosphocholine Esterase, Group-VIIA Phospholipase A2, gVIIA-PLA2, LDL-Associated Phospholipase A2, LDL-PLA(2), PAF 2-Ac
    Accession # Q13093
    Formulation Supplied as a 0.2 μm filtered solution of 20mM HAc-NaCl, 150mM NaCl, 10% Glycerol, pH 4.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    FDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGNGPYSVGCTDLMFDHTNKGTFLRLYYP SQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRLLFGSMTTPANWNSPLRPGEKYPLVVFSH GLGAFRTLYSAIGIDLASHGFIVAAVEHRDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETH IRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQ TLSEDQRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITI RGSVHQNFADFTFATGKIIGHMLKLKGDIDSNAAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEG DDENLIPGTNINTTNQHIMLQNSSGIEKYNVDHHHHHH
    Background Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position.