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C250
Recombinant Human PMM2/Phosphomannomutase 2
10ug
1200
1080
现货
国产
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C250
Recombinant Human PMM2/Phosphomannomutase 2
50ug
3520
3168
现货
国产
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C250
Recombinant Human PMM2/Phosphomannomutase 2
500ug
12320
11088
现货
国产
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C250
Recombinant Human PMM2/Phosphomannomutase 2
1mg
17600
15840
现货
国产
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Catalog# C250 Source E.coli Description Recombinant Human Phosphomannomutase 2/PMM2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser246) of Human PMM2 fused with a His tag at the C-terminus. Names Phosphomannomutase 2, PMM 2, PMM2 Accession # O15305 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYD YVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVS PIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRH VENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFSLEHHHHHHBackground Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.