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C671
Recombinant Human Protein O-linked-mannose beta-1 2-N-acetylglucosaminyltransferase 1/POMGNT1
10ug
1200
1080
现货
国产
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C671
Recombinant Human Protein O-linked-mannose beta-1 2-N-acetylglucosaminyltransferase 1/POMGNT1
50ug
3520
3168
现货
国产
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C671
Recombinant Human Protein O-linked-mannose beta-1 2-N-acetylglucosaminyltransferase 1/POMGNT1
500ug
12320
11088
现货
国产
-
C671
Recombinant Human Protein O-linked-mannose beta-1 2-N-acetylglucosaminyltransferase 1/POMGNT1
1mg
17600
15840
现货
国产
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Catalog# C671 Source HEK293 Description Recombinant Human Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1/POMGNT1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Thr660) of Human POMGNT1 fused with a polyhistidine tag at the C-terminus. Names Protein O-Linked-Mannose Beta-1,2-N-Acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1,2-N-Acetylglucosaminyltransferase I.2, GnT I.2, POMGNT1, MGAT1.2 Accession # Q8WZA1 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence LDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDE AREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDT AKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAVEAE CHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRM LRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLF PEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPG LGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFH EAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAF IRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSVKKPPSVTPIF LEPPPKEEGAPGAPEQTVDHHHHHHBackground Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).