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CF99

Recombinant Human STN1/CST complex subunit STN1/OBFC1

10ug

1200

1080

现货

国产

CF99

Recombinant Human STN1/CST complex subunit STN1/OBFC1

50ug

3520

3168

现货

国产

CF99

Recombinant Human STN1/CST complex subunit STN1/OBFC1

500ug

13440

12096

现货

国产

CF99

Recombinant Human STN1/CST complex subunit STN1/OBFC1

1mg

19200

17280

现货

国产

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  • Catalog# CF99
    Source E.coli
    Description Recombinant Human Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1/OBFC1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Phe368) of Human OBFC1 fused with a His tag at the N-terminus.
    Names CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1
    Accession # Q9H668
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 1mM DTT, pH 8.0
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPG VFLYNGHPIKQVDVLGTVIGVRERDAFYSYGVDDSTGVINCICWKKLNTESVSAAPSAARELSLT SQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATAYYKVDDPVWNIQIARMLELPTIYR KVYDQPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSFYQQELEMVESLLSLAN QPVIHSACSDQVNFKKDTTSKAIHSIFKNAIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIH RIIQQDCQKPNHMEKGCHFLHILACARLSIRPGLSEAVLQQVLELLEDQSDIVSTMEHYYTAF
    Background CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.