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C501

Recombinant Human Sulfatase Modifying Factor 1/SUMF1

10ug

840

756

现货

国产

C501

Recombinant Human Sulfatase Modifying Factor 1/SUMF1

50ug

2520

2268

现货

国产

C501

Recombinant Human Sulfatase Modifying Factor 1/SUMF1

500ug

12320

11088

现货

国产

C501

Recombinant Human Sulfatase Modifying Factor 1/SUMF1

1mg

17600

15840

现货

国产

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  • Catalog# C501
    Source HEK293
    Description Recombinant Human Sulfatase Modifying Factor 1/SUMF1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser34-Asp374) of Human SUMF1 fused with a polyhistidine tag at the C-terminus.
    Names Sulfatase-Modifying Factor 1, C-Alpha-Formylglycine-Generating Enzyme 1, SUMF1, FGE
    Accession # Q8NBK3
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10% Glycerol, pH 7.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    SQEAGTGAGAGSLAGSCGCGTPQRPGAHGSSAAAHRYSREANAPGPVPGERQLAHSKMVPIPAGV FTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLS EQVKTNIQQAVAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTE AEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYN IVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSYCYRYRCAARSQNTPDSSA SNLGFRCAADRLPTMDVHHHHHH
    Background Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.