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CD75
Recombinant Human CD266/TNFRSF12A/Fn14/TWEAKR
10ug
760
684
现货
国产
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CD75
Recombinant Human CD266/TNFRSF12A/Fn14/TWEAKR
50ug
2000
1800
现货
国产
-
CD75
Recombinant Human CD266/TNFRSF12A/Fn14/TWEAKR
500ug
12320
11088
现货
国产
-
CD75
Recombinant Human CD266/TNFRSF12A/Fn14/TWEAKR
1mg
17600
15840
现货
国产
-
CD75
Recombinant Human TNFRSF12A/Fn14/TWEAKR/CD266
10ug
760
684
现货
国产
-
CD75
Recombinant Human TNFRSF12A/Fn14/TWEAKR/CD266
50ug
2000
1800
现货
国产
-
CD75
Recombinant Human TNFRSF12A/Fn14/TWEAKR/CD266
500ug
12320
11088
现货
国产
-
CD75
Recombinant Human TNFRSF12A/Fn14/TWEAKR/CD266
1mg
17600
15840
现货
国产
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Catalog# CD75 Source Human Cells Description Recombinant Mouse Tumor necrosis factor receptor superfamily member 12A/TWEAKR/TNFRSF12 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu28-Trp79) of Mouse TNFRSF12 fused with a FC tag at the C-terminus. Names Tumor necrosis factor receptor superfamily member 12A ，Fibroblast growth factor-inducible immediate-early response protein 14 ，FGF-inducible 14 ，Fibroblast growth factor-regulated protein 2 ，Tweak-receptor ，TweakR ，Fgfrp2, Fn14 Accession # Q9CR75 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence EQAPGTSPCSSGSSWSADLDKCMDCASCPARPHSDFCLGCAAAPPAHFRLLWVDDIEGRMDEPKS CDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEV HNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVY TLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDK SRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK*Background Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important role in the inflammatory processes of rheumatoid arthritis (RA), polyarticular-course juvenile rheumatoid arthritis (JRA), and ankylosing spondylitis and the resulting joint pathology. In addition, TNF plays a role in the inflammatory process of plaque psoriasis. Elevated levels of TNF are found in involved tissues and fluids of patients with RA, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Two distinct receptors for TNF (TNFRs), a 55 kilodalton protein (p55) and a 75 kilodalton protein (p75), exist naturally as monomeric molecules on cell surfaces and in soluble forms. Biological activity of TNF is dependent upon binding to either cell surface TNFR. Recombinant Human TNFR is a dimeric soluble form of the p75 TNF receptor that can bind to two TNF molecules.