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CD76
Recombinant Human CD357/GITR/TNFRSF18
10ug
760
684
现货
国产
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CD76
Recombinant Human CD357/GITR/TNFRSF18
50ug
2000
1800
现货
国产
-
CD76
Recombinant Human CD357/GITR/TNFRSF18
500ug
12320
11088
现货
国产
-
CD76
Recombinant Human CD357/GITR/TNFRSF18
1mg
17600
15840
现货
国产
-
CD76
Recombinant Human TNFRSF18/GITR/CD357
10ug
760
684
现货
国产
-
CD76
Recombinant Human TNFRSF18/GITR/CD357
50ug
2000
1800
现货
国产
-
CD76
Recombinant Human TNFRSF18/GITR/CD357
500ug
12320
11088
现货
国产
-
CD76
Recombinant Human TNFRSF18/GITR/CD357
1mg
17600
15840
现货
国产
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Catalog# CD76 Source Human Cells Description Recombinant Mouse Tumor necrosis factor receptor superfamily member 18/GITR/TNFRSF18 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser22-His153) of Mouse TNFRSF18 fused with a FC-6His tag at the C-terminus. Names Tumor necrosis factor receptor superfamily member 18,Glucocorticoid-induced TNFR-related protein,Tnfrsf18, AITR,CD357,GITR-D,TNFRSF18 Accession # O35714 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 5X PBS.
Please aliquot the reconstituted solutionnStorage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 4 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence SVVEEPGCGPGKVQNGSGNNTRCCSLYAPGKEDCPKERCICVTPEYHCGDPQCKICKHYPCQPGQ RVESQGDIVFGFRCVACAMGTFSAGRDGHCRLWTNCSQFGFLTMFPGNKTHNAVCIPEPLPTEQY GHVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHE DPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEK TISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLD SDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH*Background Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.