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C327
Recombinant Human CD358/DR6/TNFRSF21
10ug
320
288
现货
国产
-
C327
Recombinant Human CD358/DR6/TNFRSF21
50ug
960
864
现货
国产
-
C327
Recombinant Human CD358/DR6/TNFRSF21
500ug
6160
5544
现货
国产
-
C327
Recombinant Human CD358/DR6/TNFRSF21
1mg
8800
7920
现货
国产
-
C327
Recombinant Human DR6/TNFRSF21/CD358
10ug
320
288
现货
国产
-
C327
Recombinant Human DR6/TNFRSF21/CD358
50ug
960
864
现货
国产
-
C327
Recombinant Human DR6/TNFRSF21/CD358
500ug
6160
5544
现货
国产
-
C327
Recombinant Human DR6/TNFRSF21/CD358
1mg
8800
7920
现货
国产
-
C327
Recombinant Human TNFRSF21/DR6
10ug
320
288
现货
国产
-
C327
Recombinant Human TNFRSF21/DR6
50ug
960
864
现货
国产
-
C327
Recombinant Human TNFRSF21/DR6
500ug
6160
5544
现货
国产
-
C327
Recombinant Human TNFRSF21/DR6
1mg
8800
7920
现货
国产
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Catalog# C327 Source HEK293 Description Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 21/TNFRSF21 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln42-Leu350) of Human TNFRSF21 fused with a polyhistidine tag at the C-terminus. Names Tumor Necrosis Factor Receptor Superfamily Member 21, Death Receptor 6, CD358, TNFRSF21, DR6 Accession # O75509 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence QPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKC HDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQC ARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHM ETHEVPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQ QGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLVDHHHHHHBackground Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF-α.