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CD12
Recombinant Human CD40/TNFRSF5(Fc fusion)
10ug
760
684
现货
国产
-
CD12
Recombinant Human CD40/TNFRSF5(Fc fusion)
50ug
2000
1800
现货
国产
-
CD12
Recombinant Human CD40/TNFRSF5(Fc fusion)
500ug
12320
11088
现货
国产
-
CD12
Recombinant Human CD40/TNFRSF5(Fc fusion)
1mg
17600
15840
现货
国产
-
CD12
Recombinant Human TNFRSF5/CD40(Fc fusion)
10ug
760
684
现货
国产
-
CD12
Recombinant Human TNFRSF5/CD40(Fc fusion)
50ug
2000
1800
现货
国产
-
CD12
Recombinant Human TNFRSF5/CD40(Fc fusion)
500ug
12320
11088
现货
国产
-
CD12
Recombinant Human TNFRSF5/CD40(Fc fusion)
1mg
17600
15840
现货
国产
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Catalog# CD12 Source Human Cells Description Recombinant Human CD40 is produced by our mammalian expression system. The target protein is expressed with sequence (Glu21-Arg193) of Human CD40 fused with FC and polyhistidine tag at the C-terminus. Names Tumor Necrosis Factor Receptor Superfamily member 5, B-Cell Surface Antigen CD40, Bp50, CD40L Receptor, CDw40, CD40, TNFRSF5 Accession # P25942 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence EPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDP NLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGF FSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLRVDDIEGRMDEPKSCDKTHTCPP CPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPRE EQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEM TKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVF SCSVMHEALHNHYTQKSLSLSPGKBackground CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.