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CD46
Recombinant Human CD95/TNFRSF6/FAS
10ug
760
684
现货
国产
-
CD46
Recombinant Human CD95/TNFRSF6/FAS
50ug
2280
2052
现货
国产
-
CD46
Recombinant Human CD95/TNFRSF6/FAS
500ug
12320
11088
现货
国产
-
CD46
Recombinant Human CD95/TNFRSF6/FAS
1mg
17600
15840
现货
国产
-
CD46
Recombinant Human TNFRSF6/FAS/CD95
10ug
760
684
现货
国产
-
CD46
Recombinant Human TNFRSF6/FAS/CD95
50ug
2280
2052
现货
国产
-
CD46
Recombinant Human TNFRSF6/FAS/CD95
500ug
12320
11088
现货
国产
-
CD46
Recombinant Human TNFRSF6/FAS/CD95
1mg
17600
15840
现货
国产
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Catalog# CD46 Source Human Cells Description Recombinant Human CD95/Fas/TNFRSF6 is produced by our mammalian expression system. The target protein is expressed with sequence (Gln26-Asn173) of Human FAS fused with a FC tag at the C-terminus. Names Tumor necrosis factor receptor superfamily member 6, also known as Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, APT1, FAS1, TNFRSF6 and FAS, is a single-pass type I membrane protein. Accession # P25445 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence QVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKE YTDKAHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIK ECTLTSNTKCKEEGSRSNVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMI SRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKE YKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWES NGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKH HHHHHBackground FAS is a receptor and contains three TNFR-Cys repeats and one death domain. It has been shown that FAS is involved in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. FADD (adapter molecule) recruits caspase-8 to the activated receptor, the resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. FAS-mediated apoptosis may play a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.