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C504

Recombinant Human TNFRSF10C/TRAIL R3

10ug

320

288

现货

国产

C504

Recombinant Human TNFRSF10C/TRAIL R3

50ug

960

864

现货

国产

C504

Recombinant Human TNFRSF10C/TRAIL R3

500ug

6160

5544

现货

国产

C504

Recombinant Human TNFRSF10C/TRAIL R3

1mg

8800

7920

现货

国产

C504

Recombinant Human TRAIL R3/TNFRSF10C

10ug

320

288

现货

国产

C504

Recombinant Human TRAIL R3/TNFRSF10C

50ug

960

864

现货

国产

C504

Recombinant Human TRAIL R3/TNFRSF10C

500ug

6160

5544

现货

国产

C504

Recombinant Human TRAIL R3/TNFRSF10C

1mg

8800

7920

现货

国产

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  • Catalog# C504
    Source HEK293
    Description Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 10C/TNFRSF10C produced by transfected human cells is a secreted protein with sequence(Ala26-Ala221) of Human TNFRSF10C fused with a polyhistidine tag at the C-terminus.
    Names Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Re
    Accession # O14798
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    ATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTV CKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGEVQVSNCTSWDDIQCVEEFGA NATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTP AVDHHHHHH
    Background Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.