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CH37
Recombinant Human Tripartite motif-containing protein 5/TRIM5/RNF88
10ug
1200
1080
现货
国产
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CH37
Recombinant Human Tripartite motif-containing protein 5/TRIM5/RNF88
50ug
3520
3168
现货
国产
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CH37
Recombinant Human Tripartite motif-containing protein 5/TRIM5/RNF88
500ug
12320
11088
现货
国产
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CH37
Recombinant Human Tripartite motif-containing protein 5/TRIM5/RNF88
1mg
17600
15840
现货
国产
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Catalog# CH37 Source E.coli Description Recombinant Human TRIM5 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Gln248) of Human TRIM5 fused with a 6His tag at the N-terminus. Names Tripartite motif-containing protein 5，RING finger protein 88，TRIM5，RNF88 Accession # Q9C035 Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKK SMLDKGESSCPVCRISYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDG KVICWLCERSQEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQ YDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ GSVMELLQBackground Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation