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CA36
Recombinant Human Tripeptidyl-Peptidase I/TPP1
10ug
1200
1080
现货
国产
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CA36
Recombinant Human Tripeptidyl-Peptidase I/TPP1
50ug
3520
3168
现货
国产
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CA36
Recombinant Human Tripeptidyl-Peptidase I/TPP1
500ug
12320
11088
现货
国产
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CA36
Recombinant Human Tripeptidyl-Peptidase I/TPP1
1mg
17600
15840
现货
国产
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Catalog# CA36 Source HEK293 Description Recombinant Human Tripeptidyl-Peptidase I/TPP1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser20-Pro563) of Human TPP1 fused with a 6His tag at the C-terminus. Names Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, Tripeptidyl-Peptidase I, TPP-I, TPP1, CLN2 Accession # O14773 Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 1mM GaCl2, 10%Glycerol, pH7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence SYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLEN VADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETH VVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQ DVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQY LMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTEL MKAAARGLTLLFASGDSGAGCWSVSGRHEFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISG GGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGT SASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSG PGWDPVTGWGTPNFPALLKTLLNPVDHHHHHHBackground Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).