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C262
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1
10ug
1200
1080
现货
国产
-
C262
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1
50ug
3520
3168
现货
国产
-
C262
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1
500ug
12320
11088
现货
国产
-
C262
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1
1mg
17600
15840
现货
国产
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Catalog# C262 Source E.coli Description Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Tyr133) of Human LSM1 fused with a His tag at the C-terminus. Names U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm, LSM1, CASM Accession # O15116 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFV VRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTL DEYVEHHHHHHBackground U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.