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CF41

Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C(N-polyHis)

10ug

240

216

现货

国产

CF41

Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C(N-polyHis)

50ug

600

540

现货

国产

CF41

Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C(N-polyHis)

500ug

5040

4536

现货

国产

CF41

Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C(N-polyHis)

1mg

7200

6480

现货

国产

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  • Catalog# CF41
    Source E.coli
    Description Recombinant Human Ubiquitin-Conjugating Enzyme E2 C/UBE2C is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro179) of Human UBE2C fused with a 6His tag at the N-terminus.
    Names Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C, UBCH10
    Accession # O00762
    Formulation Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, pH 7.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSHMASQNRDPAATSVAAARKGAEPSGGAARGP VGKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPT VKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPT AFKKYLQETYSKQVTSQEP
    Background Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a member of the ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. UBE2C acts as an essential factor of the anaphase, promotes complex/cyclosome (APC/C) controls progression through mitosis.