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CG01
Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C/UBCH10
10ug
760
684
现货
国产
-
CG01
Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C/UBCH10
50ug
2280
2052
现货
国产
-
CG01
Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C/UBCH10
500ug
12320
11088
现货
国产
-
CG01
Recombinant Human UBE2C/Ubiquitin-conjugating enzyme E2 C/UBCH10
1mg
17600
15840
现货
国产
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Catalog# CG01 Source E.coli Description Recombinant Human Ubiquitin-Conjugating Enzyme E2 C/UBE2C is produced with our E. coli expression system. The target protein is expressed with (Met1-Pro179) of Human UBE2C fused with a 6His tag at the N-terminus. Names Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C, UBCH10 Accession # O00762 Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MRGSHHHHHHGSMASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAF PESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDIL KEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEPBackground Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).