产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
C185
Recombinant Human UBE2H/Ubiquitin-conjugating enzyme E2 H/UbcH2
10ug
240
216
现货
国产
-
C185
Recombinant Human UBE2H/Ubiquitin-conjugating enzyme E2 H/UbcH2
50ug
600
540
现货
国产
-
C185
Recombinant Human UBE2H/Ubiquitin-conjugating enzyme E2 H/UbcH2
500ug
5040
4536
现货
国产
-
C185
Recombinant Human UBE2H/Ubiquitin-conjugating enzyme E2 H/UbcH2
1mg
7200
6480
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# C185 Source E.coli Description Recombinant Human Ubiquitin-Conjugating Enzyme E2 H/UBE2H is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Leu183) of Human UBE2H fused with a GST tag at the N-terminus. Names Ubiquitin-Conjugating Enzyme E2 H, UbcH2, Ubiquitin Carrier Protein H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Protein Ligase H, UBE2H Accession # P62256 Formulation Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKL TQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEML KMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKS SKYIAWPLQGWQATFGGGDHPPKSDLVPRGSHMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNE FVVKFYGPQGTPYEGGVWKVRVDLPDKYPFKSPSIGFMNKIFHPNIDEASGTVCLDVINQTWTAL YDLTNIFESFLPQLLAYPNPIDPLNGDAAAMYLHRPEEYKQKIKEYIQKYATEEALKEQEEGTGD SSSESSMSDFSEDEAQDMELBackground Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.