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C187
Recombinant Human UBE2T/Ubiquitin-conjugating enzyme E2 T
10ug
240
216
现货
国产
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C187
Recombinant Human UBE2T/Ubiquitin-conjugating enzyme E2 T
50ug
600
540
现货
国产
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C187
Recombinant Human UBE2T/Ubiquitin-conjugating enzyme E2 T
500ug
5040
4536
现货
国产
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C187
Recombinant Human UBE2T/Ubiquitin-conjugating enzyme E2 T
1mg
7200
6480
现货
国产
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Catalog# C187 Source E.coli Description Recombinant Human Ubiquitin-Conjugating Enzyme E2 T/UBE2T is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Val197) of Human UBE2T. Names Ubiquitin-Conjugating Enzyme E2 T, Cell Proliferation-Inducing Gene 50 Protein, Ubiquitin Carrier Protein T, Ubiquitin-Protein Ligase T, UBE2T Accession # Q9NPD8 Formulation Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTP YEKGVFKLEVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTS IQLLMSEPNPDDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVH NSTQKRKASQLVGIEKKFHPDVBackground Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.