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C591
Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog/COQ7
10ug
840
756
现货
国产
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C591
Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog/COQ7
50ug
2520
2268
现货
国产
-
C591
Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog/COQ7
500ug
12320
11088
现货
国产
-
C591
Recombinant Human Ubiquinone biosynthesis protein COQ7 homolog/COQ7
1mg
17600
15840
现货
国产
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Catalog# C591 Source Human Cells Description Recombinant Human Ubiquinone Biosynthesis Protein COQ7 Homolog/COQ7 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser37-Leu217) of Human COQ7 fused with a polyhistidine tag at the C-terminus. Names Ubiquinone Biosynthesis Protein COQ7 Homolog, Coenzyme Q Biosynthesis Protein 7 Homolog, Timing Protein Clk-1 Homolog, COQ7 Accession # Q99807 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Biological Activity IN STOCK Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence SGMTLDNISRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKDHLKKFNELM VTFRVRPTVLMPLWNVLGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEEDPEKYEE LLQLIKKFRDEELEHHDIGLDHDAELAPAYAVLKSIIQAGCRVAIYLSERLVDHHHHHHBackground Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) is a mitochondrion inner membrane and peripheral membrane protein which belongs to the COQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. COQ7 is involved in lifespan determination in ubiquinone-independent manner and also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator. Human COQ7 protein contains 179 amino acids, is mostly helical, and contains an alpha-helical membrane insertion. It has been shown that mutations in the gene are associated with increased life span. Defects of the gene slow down a variety of developmental and physiological processes, including the cell cycle, embryogenesis, post-embryonic growth, rhythmic behaviors and aging.