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C188

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCH-L1

10ug

400

360

现货

国产

C188

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCH-L1

50ug

1120

1008

现货

国产

C188

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCH-L1

500ug

6720

6048

现货

国产

C188

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCH-L1

1mg

9600

8640

现货

国产

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  • Catalog# C188
    Source E.coli
    Description Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1/UCH-L1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala223) of Human UCH-L1.
    Names Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1, UCH-L1, Neuron Cytoplasmic Protein 9.5, PGP 9.5, PGP9.5, Ubiquitin Thioesterase L1, UCHL1
    Accession # P09936
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 250mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKK QIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRA KCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLK DAAKVCREFTEREQGEVRFSAVALCKAALEHHHHHH
    Background Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.