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C189

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3

10ug

1024

921.6

现货

国产

C189

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3

50ug

3080

2772

现货

国产

C189

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3

500ug

12320

11088

现货

国产

C189

Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3

1mg

17600

15840

现货

国产

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  • Catalog# C189
    Source E.coli
    Description Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3/UCH-L3 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala230) of Human UCH-L3.
    Names Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3, UCH-L3, Ubiquitin Thioesterase L3, UCHL3
    Accession # P15374
    Formulation Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF RTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMS PEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGE TSDETLLEDAIEVCKKFMERDPDELRFNAIALSAALEHHHHHH
    Background Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.