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C189
Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3
10ug
1024
921.6
现货
国产
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C189
Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3
50ug
3080
2772
现货
国产
-
C189
Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3
500ug
12320
11088
现货
国产
-
C189
Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L3/UCH-L3
1mg
17600
15840
现货
国产
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Catalog# C189 Source E.coli Description Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3/UCH-L3 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala230) of Human UCH-L3. Names Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3, UCH-L3, Ubiquitin Thioesterase L3, UCHL3 Accession # P15374 Formulation Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF RTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMS PEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGE TSDETLLEDAIEVCKKFMERDPDELRFNAIALSAALEHHHHHHBackground Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.