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C393
Recombinant Human u-Plasminogen Activator/Urokinase
10ug
1200
1080
现货
国产
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C393
Recombinant Human u-Plasminogen Activator/Urokinase
50ug
3520
3168
现货
国产
-
C393
Recombinant Human u-Plasminogen Activator/Urokinase
500ug
12320
11088
现货
国产
-
C393
Recombinant Human u-Plasminogen Activator/Urokinase
1mg
17600
15840
现货
国产
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Catalog# C393 Source HEK293 Description Recombinant Human Urokinase-Type Plasminogen Activator is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser21-Leu431) of Human PLAU fused with a polyhistidine tag at the C-terminus. Names Urokinase-Type Plasminogen Activator, U-Plasminogen Activator, uPA, PLAU Accession # P00749 Formulation Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 2mM CaCl, 10% Glycerol, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence SNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTD TMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHD CADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLIS PCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLK IRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHREC QQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYT RVSHFLPWIRSHTKEENGLALVDHHHHHHBackground Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.