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CG72

Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT

10ug

1200

1080

现货

国产

CG72

Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT

50ug

3520

3168

现货

国产

CG72

Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT

500ug

13440

12096

现货

国产

CG72

Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT

1mg

19200

17280

现货

国产

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  • Catalog# CG72
    Source E.coli
    Description Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp309) of Human UPRT fused with a 6His tag at the N-terminus.
    Names Uracil phosphoribosyltransferase homolog, UPP, FUR1, UPRT
    Accession # Q96BW1
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl,150mM NaCl pH 8.0
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRAS RAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQL KLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKF EKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPI LSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKY FGTD
    Background UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer