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CF69
Recombinant Human Uridine Phosphorylase 1/UPP1
10ug
840
756
现货
国产
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CF69
Recombinant Human Uridine Phosphorylase 1/UPP1
50ug
2520
2268
现货
国产
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CF69
Recombinant Human Uridine Phosphorylase 1/UPP1
500ug
12320
11088
现货
国产
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CF69
Recombinant Human Uridine Phosphorylase 1/UPP1
1mg
17600
15840
现货
国产
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Catalog# CF69 Source E.coli Description Recombinant Human Uridine Phosphorylase 1/UPP1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala173) of Human UPP1 fused with a 6His tag at the N-terminus. Names UPP1 Protein, Uridine Phosphorylase 1, UPP1 Accession # Q86Y75 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 200mM NaCl, 1mM DTT, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMQRKLKVTSLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDL NKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNI EMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLSKABackground Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.