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CF48
Recombinant Human Valosin-containing protein/VCP
10ug
1200
1080
现货
国产
-
CF48
Recombinant Human Valosin-containing protein/VCP
50ug
3520
3168
现货
国产
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CF48
Recombinant Human Valosin-containing protein/VCP
500ug
13440
12096
现货
国产
-
CF48
Recombinant Human Valosin-containing protein/VCP
1mg
19200
17280
现货
国产
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Catalog# CF48 Source E.coli Description Recombinant Human Valosin-Containing Protein/VCP is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Asn589) of Human VCP fused with a 6His tag at the C-terminus. Names Transitional Endoplasmic Reticulum ATPase, TER ATPase, 15S Mg(2+)-ATPase p97 Subunit, Valosin-Containing Protein, VCP Accession # P55072 Formulation Supplied as a 0.2 μm filtered solution of 50mM Tris, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRR EAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNL FEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETHPSPYCIVAPDTVIHCEGEPIKREDEE ESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIV SQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKL ADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWA LSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPP GCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA RGGNVEHHHHHHBackground Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP participates in the formation of the transitional endoplasmic reticulum (tER) and regulates E3 ubiquitin-protein ligase activity of RNF19A.