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CG55

Recombinant Human Zinc finger protein 225//EGR1/ZNF225

10ug

1200

1080

现货

国产

CG55

Recombinant Human Zinc finger protein 225//EGR1/ZNF225

50ug

3520

3168

现货

国产

CG55

Recombinant Human Zinc finger protein 225//EGR1/ZNF225

500ug

13440

12096

现货

国产

CG55

Recombinant Human Zinc finger protein 225//EGR1/ZNF225

1mg

19200

17280

现货

国产

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  • Catalog# CG55
    Source E.coli
    Description Recombinant Human Early growth response protein 1/EGR1 is produced with our E. coli expression system. The target protein is expressed with sequence (Gln282-Ser433) of Human EGR1 fused with a 6His tag at the N-terminus.
    Names EGR-1, Early growth response protein 1, Zif268, zinc finger protein 225, NGFI-A , nerve growth factor-induced protein A,
    Accession # P18146
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMQQPSLTPLSTIKAFATQSGSQDLKALNTSYQSQLIKPSRMRKYP NRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTH TGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKSVVAS
    Background EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).