AR Biosciences USA, Inc has developed a revolutionary monoclonal antibody generation method which allows development of monoclonal antibodies without generation of hybridoma. The antibodies are developed from a broad range of antigen-specific B cells that are inaccessible to traditional hybridoma technology. This revolutionary method has successfully been applied to develop high quality rabbit and goat monoclonal antibodies.

Instead of current hybridoma generation by cell fusion methods, we directly screen antibodies from immunized rabbit or goat B cells by immunoassays such as ELISA, Western Blot, etc. and identify desired B cells. We then clone cDNA and perform recombinant antibody production using transient and stable mammalian cell expression.